Pipelle diagnostics or Pipelle biopsy is a minimally invasive method of taking endometrial cells for further examination: cytological, histological, microbiological, virological – the one that is necessary in a particular medical situation. Pipelle diagnostics of endometrium is vacuum aspiration taking of cells with the safest possible impact on the uterine cavity. The procedure is performed on an outpatient basis and does not require hospitalisation, is virtually painless and the patient does not require anaesthesia in the vast majority of cases.
Indications for Pipelle diagnostics
Pipelle diagnostics of endometrium in gynaecology and reproductology is recommended in the same cases as an endometrial biopsy using other methods, namely:
• preparations for IVF;
• monitoring and evaluation of the endometrium disease treatment;
• uterine bleeding;
• history of failed IVF programmes;
• suspected endometrial cancer.
Endometrial Pipelle biopsy may be recommended after extended colposcopy, ultrasound examination of the small pelvis' organs and endoscopic vaginal tests, the results of which confirm the need for such examination.
Pipelle diagnostics at MAMA Riga Clinic
Endometrial Pipelle biopsy in MAMA Riga Clinic may be recommended to patients with diagnosed endometrial pathology, suspected endometrial pathology, in cases of repeated miscarriage, in cases of embryo implantation failure as part of the past in vitro fertilisation programme.
Healthy endometrium is of great value for the occurring and safe carrying of pregnancy. The embryo attaches itself to the walls of the uterus covered with the layer of endometrium. The state of endometrium is also of great importance during pregnancy: during the carrying period, the endometrium shows increase in the number of glands and blood vessels, which are part of the placenta delivering oxygen and nutrients to the embryo.
The results of Pipelle biopsy help our experts diagnose possible pathology of the endometrium and assign and perform the necessary therapy in order to prepare the endometrium for pregnancy and minimise the risks of spontaneous interruption in the early stages.
Pipelle biopsy is a minimally invasive procedure, but it is intervention into the uterine cavity nonetheless. We assign this procedure only if absolutely necessary. Our Clinic's equipment and expertise of our specialists allow us to perform a biopsy while minimally traumatising the uterus and uterine cervix. This is a brief and virtually painless procedure, and usually we perform Pipelle diagnostics without the use of anaesthesia. However, in some cases it may be decided in favour of anaesthesia – in the absence of medical contraindications and if desired by the patient.
The endometrial biopsy is usually performed at the end of the menstrual cycle; however the exact date of the procedure will be assigned by your consultant physician. Preparations for Pipelle diagnostics include blood tests, including coagulation, HIV, syphilis and hepatitis analyses and examination of gynaecological swabs for flora, bacterial inoculation, and hidden infections. Pipelle biopsy is not assigned in cases of infectious and inflammatory diseases. The examination is only possible after a women's complete recovery.